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Found 694 from Imperial College
TargetD(3) dopamine receptor(Homo sapiens (Human))
Imperial College

Curated by ChEMBL
LigandPNGBDBM50020217((4aR,10bR)-4-propyl-3,4,4a,5,6,10b-hexahydro-2H-na...)
Affinity DataKi:  0.200nMAssay Description:Agonistic activity at DRD3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Imperial College

Curated by PDSP Ki Database
LigandPNGBDBM50354849(CCI-18781 | Cutivate | FLUTICASONE PROPIONATE | Fl...)
Affinity DataKi:  0.238nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetGlucocorticoid receptor(Homo sapiens (Human))
Imperial College

Curated by PDSP Ki Database
LigandPNGBDBM86696(des-CIC | desisobutyryl-ciclesonide)
Affinity DataKi:  0.310nMMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Imperial College

Curated by ChEMBL
LigandPNGBDBM50414563(CHEMBL559873)
Affinity DataKi:  0.631nMAssay Description:Binding affinity to human DRD3 receptor by GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Rattus norvegicus (Rat))
Imperial College

Curated by ChEMBL
LigandPNGBDBM50331549(CHEMBL567286 | [11C]-3-(2-oxo-3-(2-(4-(trifluorome...)
Affinity DataKi:  0.794nMAssay Description:Antagonistic activity at rat DRD3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Imperial College

Curated by ChEMBL
LigandPNGBDBM50331549(CHEMBL567286 | [11C]-3-(2-oxo-3-(2-(4-(trifluorome...)
Affinity DataKi:  0.794nMAssay Description:Antagonistic activity at human DRD3 receptor by filtration binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxytocin receptor(Homo sapiens (Human))
Imperial College

Curated by ChEMBL
LigandPNGBDBM50205990(CHEMBL395429 | OXYTOCIN)
Affinity DataKi:  1.20nMAssay Description:Displacement of [3H]OT from human mammary gland oxytocin receptor expressed in HEK293 cell membrane after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Imperial College

Curated by ChEMBL
LigandPNGBDBM50414574(CHEMBL563580)
Affinity DataKi:  1.26nMAssay Description:Binding affinity to human DRD3 receptor by GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Imperial College

Curated by ChEMBL
LigandPNGBDBM50411402(CHEMBL244946)
Affinity DataKi:  1.58nMAssay Description:Binding affinity to human DRD3 receptor by GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Imperial College

Curated by ChEMBL
LigandPNGBDBM50414578(CHEMBL558058)
Affinity DataKi:  1.58nMAssay Description:Binding affinity to human DRD3 receptor by GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Imperial College

Curated by ChEMBL
LigandPNGBDBM50044777(Arginine Vasopressin | Beta-Hypophamine | CHEBI:34...)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]AVP from human liver vasopressin V1a receptor expressed in HEK293 cell membrane after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1b receptor(Homo sapiens (Human))
Imperial College

Curated by ChEMBL
LigandPNGBDBM50044777(Arginine Vasopressin | Beta-Hypophamine | CHEBI:34...)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]AVP from human vasopressin V1b receptor expressed in HEK293 cell membrane after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Imperial College

Curated by ChEMBL
LigandPNGBDBM50414570(CHEMBL563635)
Affinity DataKi:  2.51nMAssay Description:Binding affinity to human DRD3 receptor by GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Imperial College

Curated by ChEMBL
LigandPNGBDBM50414403(CHEMBL560177)
Affinity DataKi:  2.51nMAssay Description:Binding affinity to human DRD3 receptor by GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Imperial College

Curated by ChEMBL
LigandPNGBDBM50414572(CHEMBL563860)
Affinity DataKi:  2.51nMAssay Description:Binding affinity to human DRD3 receptor by GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Imperial College

Curated by ChEMBL
LigandPNGBDBM50414557(CHEMBL562464)
Affinity DataKi:  2.51nMAssay Description:Binding affinity to human DRD3 receptor by GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Imperial College

Curated by ChEMBL
LigandPNGBDBM50414563(CHEMBL559873)
Affinity DataKi:  3.16nMAssay Description:Binding affinity to human DRD2 receptor by GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Imperial College

Curated by ChEMBL
LigandPNGBDBM50414555(CHEMBL565075)
Affinity DataKi:  3.16nMAssay Description:Binding affinity to human DRD3 receptor by GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Imperial College

Curated by ChEMBL
LigandPNGBDBM50370572(CHEMBL85606 | SB-277011)
Affinity DataKi:  3.98nMAssay Description:Binding affinity to human DRD3 receptor by GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Imperial College

Curated by ChEMBL
LigandPNGBDBM50414572(CHEMBL563860)
Affinity DataKi:  3.98nMAssay Description:Binding affinity to human DRD2 receptor by GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Imperial College

Curated by ChEMBL
LigandPNGBDBM50414566(CHEMBL563435)
Affinity DataKi:  5.01nMAssay Description:Binding affinity to human DRD3 receptor by GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Imperial College

Curated by ChEMBL
LigandPNGBDBM50414574(CHEMBL563580)
Affinity DataKi:  5.01nMAssay Description:Binding affinity to human DRD2 receptor by GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxytocin receptor(Homo sapiens (Human))
Imperial College

Curated by ChEMBL
LigandPNGBDBM50044777(Arginine Vasopressin | Beta-Hypophamine | CHEBI:34...)
Affinity DataKi:  6nMAssay Description:Displacement of [3H]OT from human mammary gland oxytocin receptor expressed in HEK293 cell membrane after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Imperial College

Curated by ChEMBL
LigandPNGBDBM50414565(CHEMBL563274)
Affinity DataKi:  6.31nMAssay Description:Binding affinity to human DRD3 receptor by GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Imperial College

Curated by ChEMBL
LigandPNGBDBM50020217((4aR,10bR)-4-propyl-3,4,4a,5,6,10b-hexahydro-2H-na...)
Affinity DataKi:  6.31nMAssay Description:Agonistic activity at DRD2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Imperial College

Curated by PDSP Ki Database
LigandPNGBDBM18207((1R,2S,10S,11S,13R,14R,15S,17S)-1-fluoro-14,17-dih...)
Affinity DataKi:  6.70nMMore data for this Ligand-Target Pair
TargetGlycylpeptide N-tetradecanoyltransferase(Plasmodium falciparum (isolate 3D7))
Imperial College

Curated by ChEMBL
LigandPNGBDBM50496902(CHEMBL3237438)
Affinity DataKi:  8nMAssay Description:Inhibition of Plasmodium falciparum N-myristoyltransferase by CPM fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Imperial College

Curated by ChEMBL
LigandPNGBDBM50414567(CHEMBL562948)
Affinity DataKi:  10nMAssay Description:Binding affinity to human DRD3 receptor by GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Imperial College

Curated by ChEMBL
LigandPNGBDBM50211726(CHEMBL403896 | FR-901451)
Affinity DataKi:  10nMAssay Description:Inhibition of human leukocyte elastaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Imperial College

Curated by ChEMBL
LigandPNGBDBM50080264(1N-[21-benzyl-29-[(Z)-ethylidene]-13,14,23-trihydr...)
Affinity DataKi:  12nMAssay Description:Inhibition of human leukocyte elastaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Imperial College

Curated by ChEMBL
LigandPNGBDBM50414571(CHEMBL563563)
Affinity DataKi:  12.6nMAssay Description:Binding affinity to human DRD3 receptor by GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycylpeptide N-tetradecanoyltransferase(Plasmodium falciparum (isolate 3D7))
Imperial College

Curated by ChEMBL
LigandPNGBDBM50496912(CHEMBL3237422)
Affinity DataKi:  15nMAssay Description:Inhibition of Plasmodium falciparum N-myristoyltransferase by CPM fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlycylpeptide N-tetradecanoyltransferase(Plasmodium falciparum (isolate 3D7))
Imperial College

Curated by ChEMBL
LigandPNGBDBM50496896(CHEMBL3237425)
Affinity DataKi:  15nMAssay Description:Inhibition of Plasmodium falciparum N-myristoyltransferase by CPM fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Imperial College

Curated by ChEMBL
LigandPNGBDBM50414556(CHEMBL564930)
Affinity DataKi:  15.8nMAssay Description:Binding affinity to human DRD3 receptor by GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Imperial College

Curated by ChEMBL
LigandPNGBDBM50414554(CHEMBL551927)
Affinity DataKi:  15.8nMAssay Description:Binding affinity to human DRD2 receptor by GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Imperial College

Curated by ChEMBL
LigandPNGBDBM50414554(CHEMBL551927)
Affinity DataKi:  19.9nMAssay Description:Binding affinity to human DRD3 receptor by GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Imperial College

Curated by ChEMBL
LigandPNGBDBM50414578(CHEMBL558058)
Affinity DataKi:  19.9nMAssay Description:Binding affinity to human DRD2 receptor by GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Imperial College

Curated by ChEMBL
LigandPNGBDBM50414581(CHEMBL560270)
Affinity DataKi:  19.9nMAssay Description:Binding affinity to human DRD3 receptor by GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Imperial College

Curated by ChEMBL
LigandPNGBDBM50205990(CHEMBL395429 | OXYTOCIN)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]AVP from human liver vasopressin V1a receptor expressed in HEK293 cell membrane after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycylpeptide N-tetradecanoyltransferase 1(Homo sapiens (Human))
Imperial College

Curated by ChEMBL
LigandPNGBDBM50148269(CHEMBL3770219)
Affinity DataKi:  20nMAssay Description:Binding affinity to human N-myristoyltransferase by fluorescence analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Imperial College

Curated by ChEMBL
LigandPNGBDBM50311138(CHEMBL1077421)
Affinity DataKi:  21nMAssay Description:Inhibition of human leukocyte elastase by substrate hydrolysis based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycylpeptide N-tetradecanoyltransferase 1(Homo sapiens (Human))
Imperial College

Curated by ChEMBL
LigandPNGBDBM50135488(CHEMBL3754571)
Affinity DataKi:  24nMAssay Description:Inhibition of human NMT1 by 7-diethylamine-3-(4'maleimidylphenyl)-4-methylcoumarin based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Imperial College

Curated by ChEMBL
LigandPNGBDBM50414570(CHEMBL563635)
Affinity DataKi:  25.1nMAssay Description:Binding affinity to human DRD2 receptor by GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Imperial College

Curated by ChEMBL
LigandPNGBDBM50414579(CHEMBL564948)
Affinity DataKi:  25.1nMAssay Description:Binding affinity to human DRD3 receptor by GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Imperial College

Curated by ChEMBL
LigandPNGBDBM50414564(CHEMBL562833)
Affinity DataKi:  25.1nMAssay Description:Binding affinity to human DRD3 receptor by GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Imperial College

Curated by ChEMBL
LigandPNGBDBM50414555(CHEMBL565075)
Affinity DataKi:  25.1nMAssay Description:Binding affinity to human DRD2 receptor by GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Imperial College

Curated by ChEMBL
LigandPNGBDBM50414558(CHEMBL556496)
Affinity DataKi:  25.1nMAssay Description:Binding affinity to human DRD2 receptor by GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Imperial College

Curated by ChEMBL
LigandPNGBDBM50414557(CHEMBL562464)
Affinity DataKi:  25.1nMAssay Description:Binding affinity to human DRD2 receptor by GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycylpeptide N-tetradecanoyltransferase(Plasmodium falciparum (isolate 3D7))
Imperial College

Curated by ChEMBL
LigandPNGBDBM50496904(CHEMBL3237412)
Affinity DataKi:  26nMAssay Description:Inhibition of Plasmodium falciparum N-myristoyltransferase by CPM fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlycylpeptide N-tetradecanoyltransferase 1(Homo sapiens (Human))
Imperial College

Curated by ChEMBL
LigandPNGBDBM50027680(CHEMBL3357975)
Affinity DataKi:  27nMAssay Description:Inhibition of human NMT1 using GSNKSKPKDASQRRR-NH2 as substrate by CPM fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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